AstraZeneca Pharma India Limited ('AstraZeneca'), a leading science-led biopharmaceutical company (BSE : 506820, NSE : ASTRAZEN) and Sun Pharmaceutical Industries Limited (Reuters: SUN.BO, Bloomberg: SUNP IN, NSE: SUNPHARMA, BSE: 524715, "Sun Pharma" and includes its subsidiaries and/or associate companies), today announced a second brand partnership for Sodium Zirconium Cyclosilicate (SZC) in India. This exclusive agreement is aimed at further accelerating availability of SZC, an innovative and highly effective treatment for Hyperkalaemia to more patients across India.
Under the agreement, both companies will promote, market & distribute SZC in India under different brand names; AstraZeneca will market SZC as Lokelma® whereas Sun Pharma will promote and distribute the therapy as Gimliand®. AstraZeneca will retain the intellectual property rights to SZC and hold the Marketing Authorization along with the import license of the molecule.
Praveen Rao Akkinepally, Country President & Managing Director AstraZeneca Pharma India Limited said, "At AstraZeneca, we aim to transform care with a focus on increasing early screening, diagnosis, and adoption of guideline-directed medical therapy to improve patient outcomes. This partnership with Sun Pharma for SZC reaffirms AstraZeneca's purpose to deliver innovative, life-changing medicines to patients with Hyperkalaemia across India, coupled with building robust pathways to reach patients in need. With this step, we are poised to significantly expand the reach of this vital therapy and help address the disease burden".
Kirti Ganorkar, Managing Director, Sun Pharmaceutical Industries Limited said, "We are delighted to join hands with AstraZeneca to address the growing challenge of Hyperkalaemia in India. The addition of SZC to our portfolio underscores our unwavering commitment to improving the care of patients with chronic kidney disease. As India's largest pharmaceutical company and a leader in this therapy area, we remain focused on expanding access to innovative treatments that empower healthcare professionals and enhance the quality of life for patients."
Hyperkalaemia is a clinically significant condition that disproportionately affects patients with chronic kidney disease (CKD) and those with heart failure (HF) receiving renin-angiotensin-aldosterone system (RAAS) inhibitor therapy, which can elevate serum potassium levels. Prevalence estimates suggest that Hyperkalaemia occurs in up to 50% of patients with CKD and 42% of patients with chronic HF. To manage or prevent recurrence, RAAS inhibitor therapy is often reduced or discontinued, which may compromise cardiorenal outcomes and increase mortality risk. In India, mortality associated with Hyperkalaemia has been reported at 22.2%. Sodium zirconium cyclosilicate (SZC) offers a rapid, effective, and generally well‑tolerated treatment option for the management of Hyperkalaemia.
Sun Pharma is the largest pharmaceutical company in India, with an 8.3% market share10 and ranks No. 1 in prescriptions across 13 different doctor categories11. With a 15,000-strong field force, the company leads in chronic therapies and maintains a strong presence in the acute segment.
Building upon AstraZeneca's ambition to advance science, transform care and help manage life threatening conditions like Hyperkalaemia, this strategic step is a significant move in improving the management of Hyperkalaemia in India; promising enhanced availability to a crucial treatment and ultimately contributing to better patient outcomes nationwide.
Shares of AstraZeneca Pharma India Limited was last trading in BSE at Rs. 9132.00 as compared to the previous close of Rs. 9155.10. The total number of shares traded during the day was 496 in over 164 trades.
The stock hit an intraday high of Rs. 9392.80 and intraday low of 9104.25. The net turnover during the day was Rs. 4552477.00.
Shares of Sun Pharmaceutical Industries Limited was last trading in BSE at Rs. 1763.70 as compared to the previous close of Rs. 1756.40. The total number of shares traded during the day was 22392 in over 2738 trades.
The stock hit an intraday high of Rs. 1769.15 and intraday low of 1747.60. The net turnover during the day was Rs. 39348202.00.